Activation of GPR40 Suppresses AGE-Induced Reduction of Type II Collagen and Aggrecan in Human SW1353 Chondrocytes

INTRODUCTION: Osteoarthritis (OA) is an age-related chronic degenerative disease. Accumulation of advanced glycation end products (AGEs) induces degradation of the articular extracellular matrix (ECM) and is considered a critical step toward the development and progression of OA. GPR40 is a well-kno...

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Detalles Bibliográficos
Autores principales: Gu, Jiaxiang, Lin, Hongsheng, Zhang, Yiyuan, Xu, Tao, Wang, Tianliang, Xue, Xiawei, Zhang, Wenzhong, Liu, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305341/
https://www.ncbi.nlm.nih.gov/pubmed/32606604
http://dx.doi.org/10.2147/DDDT.S239273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305341/
https://www.ncbi.nlm.nih.gov/pubmed/32606604
http://dx.doi.org/10.2147/DDDT.S239273

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