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Activation of GPR40 Suppresses AGE-Induced Reduction of Type II Collagen and Aggrecan in Human SW1353 Chondrocytes

INTRODUCTION: Osteoarthritis (OA) is an age-related chronic degenerative disease. Accumulation of advanced glycation end products (AGEs) induces degradation of the articular extracellular matrix (ECM) and is considered a critical step toward the development and progression of OA. GPR40 is a well-kno...

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Detalles Bibliográficos
Autores principales:	Gu, Jiaxiang, Lin, Hongsheng, Zhang, Yiyuan, Xu, Tao, Wang, Tianliang, Xue, Xiawei, Zhang, Wenzhong, Liu, Hongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305341/ https://www.ncbi.nlm.nih.gov/pubmed/32606604 http://dx.doi.org/10.2147/DDDT.S239273

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