Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion

OBJECTIVE: Deletion of Translin (Tsn) from mice induces an unusual metabolic profile characterized by robust adiposity, normal body weight and glucose tolerance. Translin (TN) protein and its partner, trax (TX), form the TN/TX microRNA-degrading enzyme. Since the microRNA system plays a prominent ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Xiuping, Shah, Aparna P., Li, Zhi, Li, Mengni, Tamashiro, Kellie L., Baraban, Jay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305343/
https://www.ncbi.nlm.nih.gov/pubmed/32408014
http://dx.doi.org/10.1016/j.molmet.2020.101013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305343/
https://www.ncbi.nlm.nih.gov/pubmed/32408014
http://dx.doi.org/10.1016/j.molmet.2020.101013

Ejemplares similares