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Implications of Error-Prone Long-Read Whole-Genome Shotgun Sequencing on Characterizing Reference Microbiomes

Long-read sequencing techniques, such as the Oxford Nanopore Technology, can generate reads that are tens of kilobases in length and are therefore particularly relevant for microbiome studies. However, owing to the higher per-base error rates than typical short-read sequencing, the application of lo...

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Detalles Bibliográficos
Autores principales: Hu, Yu, Fang, Li, Nicholson, Christopher, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305381/
https://www.ncbi.nlm.nih.gov/pubmed/32563152
http://dx.doi.org/10.1016/j.isci.2020.101223