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The regulation of Oct4 in human gingival fibroblasts stimulated by cyclosporine A: Preliminary observations

BACKGROUND/PURPOSE: Oct4, a key transcription factor, could reprogram human somatic fibroblasts into embryonic stem cell-like pluripotent cells. The exact mechanism of cyclosporine A (CsA)-induced gingival overgrowth is still unclear. The aim of this study was to investigate the effects of CsA on th...

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Detalles Bibliográficos
Autores principales: Yu, Cheng-Chia, Liu, Chia-Ming, Lin, Tai-Chen, Su, Ni-Yu, Yang, Li-Chiu, Chang, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305449/
https://www.ncbi.nlm.nih.gov/pubmed/32595898
http://dx.doi.org/10.1016/j.jds.2019.10.001