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Exportin 1 inhibition as antiviral therapy

Coronavirus 2019 (COVID-19; caused by Severe Acute Respiratory Syndrome Coronavirus 2; SARS-CoV-2) is a currently global health problem. Previous studies showed that blocking nucleocytoplasmic transport with exportin 1 (XPO1) inhibitors originally developed as anticancer drugs can quarantine key vir...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Hafiz, Zonder, Jeffrey A., Azmi, Asfar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305737/
https://www.ncbi.nlm.nih.gov/pubmed/32569833
http://dx.doi.org/10.1016/j.drudis.2020.06.014