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RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus

SARS-CoV-2 genomic and subgenomic RNA (sgRNA) transcripts hijack the host cell's machinery. Subcellular localization of its viral RNA could, thus, play important roles in viral replication and host antiviral immune response. We perform computational modeling of SARS-CoV-2 viral RNA subcellular...

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Detalles Bibliográficos
Autores principales: Wu, Kevin E., Fazal, Furqan M., Parker, Kevin R., Zou, James, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305881/
https://www.ncbi.nlm.nih.gov/pubmed/32673562
http://dx.doi.org/10.1016/j.cels.2020.06.008