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S-allylmercaptocysteine inhibits mucin overexpression and inflammation via MAPKs and PI3K-Akt signaling pathways in acute respiratory distress syndrome

Cytokine storm is an important cause of acute respiratory distress syndrome and multiple organ failure. Excessive secretion and accumulation of mucins on the surface of airway cause airway obstruction and exacerbate lung infections. MUC5AC and MUC5B are the main secreted mucins and overexpressed in...

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Detalles Bibliográficos
Autores principales: An, Lulu, Zhao, Jianxiong, Sun, Xiao, Zhou, Yingying, Zhao, Zhongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305891/
https://www.ncbi.nlm.nih.gov/pubmed/32574825
http://dx.doi.org/10.1016/j.phrs.2020.105032