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Population pharmacokinetics and target attainment of ciprofloxacin in critically ill patients
PURPOSE: To develop and validate a population pharmacokinetic model of ciprofloxacin intravenously in critically ill patients, and determine target attainment to provide guidance for more effective regimens. METHODS: Non-linear mixed-effects modelling was used for the model development and covariate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306030/ https://www.ncbi.nlm.nih.gov/pubmed/32307575 http://dx.doi.org/10.1007/s00228-020-02873-5 |