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Production and secretion dynamics of prokaryotic Penicillin G acylase in Pichia pastoris

To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory process should be understood and optimised by circumventing bottlenecks. Typically, little or no attention has been paid to the fate of newly s...

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Detalles Bibliográficos
Autores principales: Borčinová, Martina, Raschmanová, Hana, Zamora, Iwo, Looser, Verena, Marešová, Helena, Hirsch, Sven, Kyslík, Pavel, Kovar, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306039/
https://www.ncbi.nlm.nih.gov/pubmed/32424437
http://dx.doi.org/10.1007/s00253-020-10669-x