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Genetic Counseling and Germline Testing in the Era of Tumor Sequencing: A Cohort Study

BACKGROUND: The clinical impact of addressing potential germline alterations from tumor-only next-generation sequencing (NGS) is not well characterized. Current guidelines for cancer genetic testing may miss clinically actionable germline changes, which may have important implications for cancer scr...

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Detalles Bibliográficos
Autores principales: Klek, Stefan, Heald, Brandie, Milinovich, Alex, Ni, Ying, Abraham, Jame, Mahdi, Haider, Estfan, Bassam, Khorana, Alok A, Bolwell, Brian J, Grivas, Petros, Sohal, Davendra P S, Funchain, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306190/
https://www.ncbi.nlm.nih.gov/pubmed/32596633
http://dx.doi.org/10.1093/jncics/pkaa018