In silico design of two novel fusion proteins, p28-IL-24 and p28-M4, targeted to breast cancer cells

BACKGROUND AND PURPOSE: An anticancer peptide P28, has shown to be cytolethal on various cancer cells including breast cancer. Moreover, p28 can be also used as a targeting moiety in the structure of fusion proteins. IL-24 (or its truncated form, M4) is a cytokine with anticancer activity against a...

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Detalles Bibliográficos
Autores principales: Ghavimi, Reza, Mohammadi, Elmira, Akbari, Vajihe, Shafiee, Fatemeh, Jahanian-Najafabadi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306244/
https://www.ncbi.nlm.nih.gov/pubmed/32582360
http://dx.doi.org/10.4103/1735-5362.283820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306244/
https://www.ncbi.nlm.nih.gov/pubmed/32582360
http://dx.doi.org/10.4103/1735-5362.283820

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