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In silico design of two novel fusion proteins, p28-IL-24 and p28-M4, targeted to breast cancer cells
BACKGROUND AND PURPOSE: An anticancer peptide P28, has shown to be cytolethal on various cancer cells including breast cancer. Moreover, p28 can be also used as a targeting moiety in the structure of fusion proteins. IL-24 (or its truncated form, M4) is a cytokine with anticancer activity against a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306244/ https://www.ncbi.nlm.nih.gov/pubmed/32582360 http://dx.doi.org/10.4103/1735-5362.283820 |