Design, construction, and expression of recombinant human interferon beta gene in CHO-s cell line using EBV-based expression system

BACKGROUND AND PURPOSE: Codon optimization has been considered as a powerful strategy to increase the expression level of protein therapeutics in mammalian cells. As an empirical approach to study the effects of the codon usage and GC content on heterologous gene expression in suspension adapted Chi...

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Detalles Bibliográficos
Autores principales: Shayesteh, Mohadeseh, Ghasemi, Fahimeh, Tabandeh, Fatemeh, Yakhchali, Bagher, Shakibaie, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306247/
https://www.ncbi.nlm.nih.gov/pubmed/32582354
http://dx.doi.org/10.4103/1735-5362.283814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306247/
https://www.ncbi.nlm.nih.gov/pubmed/32582354
http://dx.doi.org/10.4103/1735-5362.283814

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