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Design, construction, and expression of recombinant human interferon beta gene in CHO-s cell line using EBV-based expression system
BACKGROUND AND PURPOSE: Codon optimization has been considered as a powerful strategy to increase the expression level of protein therapeutics in mammalian cells. As an empirical approach to study the effects of the codon usage and GC content on heterologous gene expression in suspension adapted Chi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306247/ https://www.ncbi.nlm.nih.gov/pubmed/32582354 http://dx.doi.org/10.4103/1735-5362.283814 |