A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations

Creatinine is the most common clinical biomarker of renal function. As a substrate for renal transporters, its secretion is susceptible to inhibition by drugs, resulting in transient increase in serum creatinine and false impression of damage to kidney. Novel physiologically based models for creatin...

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Detalles Bibliográficos
Autores principales: Scotcher, Daniel, Arya, Vikram, Yang, Xinning, Zhao, Ping, Zhang, Lei, Huang, Shiew‐Mei, Rostami‐Hodjegan, Amin, Galetin, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306622/
https://www.ncbi.nlm.nih.gov/pubmed/32441889
http://dx.doi.org/10.1002/psp4.12509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306622/
https://www.ncbi.nlm.nih.gov/pubmed/32441889
http://dx.doi.org/10.1002/psp4.12509

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