MYC protein stability is negatively regulated by BRD4

The protooncogene MYC regulates a variety of cellular processes, including proliferation and metabolism. Maintaining MYC at homeostatic levels is critical to normal cell function; overexpression drives many cancers. MYC stability is regulated through phosphorylation: phosphorylation at Thr58 signals...

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Detalles Bibliográficos
Autores principales: Devaiah, Ballachanda N., Mu, Jie, Akman, Ben, Uppal, Sheetal, Weissman, Jocelyn D., Cheng, Dan, Baranello, Laura, Nie, Zuqin, Levens, David, Singer, Dinah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306749/
https://www.ncbi.nlm.nih.gov/pubmed/32482868
http://dx.doi.org/10.1073/pnas.1919507117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306749/
https://www.ncbi.nlm.nih.gov/pubmed/32482868
http://dx.doi.org/10.1073/pnas.1919507117

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