HTLV-1 induces T cell malignancy and inflammation by viral antisense factor-mediated modulation of the cytokine signaling

Human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of a T cell neoplasm and several inflammatory diseases. A viral gene, HTLV-1 bZIP factor (HBZ), induces pathogenic Foxp3-expressing T cells and triggers systemic inflammation and T cell lymphoma in transgenic mice, indicating its sig...

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Detalles Bibliográficos
Autores principales: Higuchi, Yusuke, Yasunaga, Jun-ichirou, Mitagami, Yu, Tsukamoto, Hirotake, Nakashima, Kazutaka, Ohshima, Koichi, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306771/
https://www.ncbi.nlm.nih.gov/pubmed/32471947
http://dx.doi.org/10.1073/pnas.1922884117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306771/
https://www.ncbi.nlm.nih.gov/pubmed/32471947
http://dx.doi.org/10.1073/pnas.1922884117

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