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Dedifferentiation: the return road to repair the intestinal epithelium

In the March 5 issue of Cell Stem Cell, (Murata K et al. Cell Stem Cell. 26(377–390):e376 2020) reported that intestinal stem cell recovery after injury is principally through Ascl2-dependent dedifferentiation of absorptive and secretory precursors in mice. This study provides evidence for robust re...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Xiong, Xiaochen, Chen, Ye-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306829/
https://www.ncbi.nlm.nih.gov/pubmed/32588148
http://dx.doi.org/10.1186/s13619-020-00048-2