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scClassify: sample size estimation and multiscale classification of cells using single and multiple reference

Automated cell type identification is a key computational challenge in single‐cell RNA‐sequencing (scRNA‐seq) data. To capitalise on the large collection of well‐annotated scRNA‐seq datasets, we developed scClassify, a multiscale classification framework based on ensemble learning and cell type hier...

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Detalles Bibliográficos
Autores principales: Lin, Yingxin, Cao, Yue, Kim, Hani Jieun, Salim, Agus, Speed, Terence P, Lin, David M, Yang, Pengyi, Yang, Jean Yee Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306901/
https://www.ncbi.nlm.nih.gov/pubmed/32567229
http://dx.doi.org/10.15252/msb.20199389