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Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis
OBJECTIVE: Familial adenomatous polyposis (FAP) is characterised by the development of hundreds to thousands of adenomas at different evolutionary stages in the colon and rectum that will inevitably progress to adenocarcinomas if left untreated. Here, we investigated the genetic alterations and tran...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306982/ https://www.ncbi.nlm.nih.gov/pubmed/31744909 http://dx.doi.org/10.1136/gutjnl-2019-319438 |