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Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis

OBJECTIVE: Familial adenomatous polyposis (FAP) is characterised by the development of hundreds to thousands of adenomas at different evolutionary stages in the colon and rectum that will inevitably progress to adenocarcinomas if left untreated. Here, we investigated the genetic alterations and tran...

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Detalles Bibliográficos
Autores principales: Li, Jingyun, Wang, Rui, Zhou, Xin, Wang, Wendong, Gao, Shuai, Mao, Yunuo, Wu, Xinglong, Guo, Limei, Liu, Haijing, Wen, Lu, Fu, Wei, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306982/
https://www.ncbi.nlm.nih.gov/pubmed/31744909
http://dx.doi.org/10.1136/gutjnl-2019-319438