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Oligomerization of the Vesicular Stomatitis Virus Phosphoprotein Is Dispensable for mRNA Synthesis but Facilitates RNA Replication

Nonsegmented negative-strand (NNS) RNA viruses possess a ribonucleoprotein template in which the genomic RNA is sequestered within a homopolymer of nucleocapsid protein (N). The viral RNA-dependent RNA polymerase (RdRP) resides within an approximately 250-kDa large protein (L), along with unconventi...

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Detalles Bibliográficos
Autores principales: Bloyet, Louis-Marie, Morin, Benjamin, Brusic, Vesna, Gardner, Erica, Ross, Robin A., Vadakkan, Tegy, Kirchhausen, Tomas, Whelan, Sean P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307139/
https://www.ncbi.nlm.nih.gov/pubmed/32321813
http://dx.doi.org/10.1128/JVI.00115-20