Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5

During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into “infectious” virus particles. Copyback DVGs are the primary inducers of innate intracellular responses, including the interferon (IFN) response. While DVGs c...

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Detalles Bibliográficos
Autores principales: Wignall-Fleming, Elizabeth B., Vasou, Andri, Young, Dan, Short, John A. L., Hughes, David J., Goodbourn, Steve, Randall, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307174/
https://www.ncbi.nlm.nih.gov/pubmed/32295916
http://dx.doi.org/10.1128/JVI.00246-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307174/
https://www.ncbi.nlm.nih.gov/pubmed/32295916
http://dx.doi.org/10.1128/JVI.00246-20

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