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BRD2 induces drug resistance through activation of the RasGRP1/Ras/ERK signaling pathway in adult T‐cell lymphoblastic lymphoma

BACKGROUND: Adult patients with T‐cell lymphoblastic lymphoma (T‐LBL) are treated with high‐intensity chemotherapy regimens, but the response rate is still unsatisfactory because of frequent drug resistance. We aimed to investigate the potential mechanisms of drug resistance in adults with T‐LBL. ME...

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Detalles Bibliográficos
Autores principales: Tian, Xiao‐Peng, Cai, Jun, Ma, Shu‐Yun, Fang, Yu, Huang, Hui‐Qiang, Lin, Tong‐Yu, Rao, Hui‐Lan, Li, Mei, Xia, Zhong‐Jun, Kang, Tie‐Bang, Xie, Dan, Cai, Qing‐Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307265/
https://www.ncbi.nlm.nih.gov/pubmed/32459053
http://dx.doi.org/10.1002/cac2.12039