Translational Reprogramming Marks Adaptation to Asparagine Restriction in Cancer

While amino acid restriction remains an attractive strategy for cancer therapy, metabolic adaptations limit its effectiveness. Here we demonstrate a role of translational reprogramming in the survival of asparagine-restricted cancer cells. Asparagine limitation in melanoma and pancreatic cancer cell...

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Detalles Bibliográficos
Autores principales: Pathria, Gaurav, Lee, Joo Sang, Hasnis, Erez, Tandoc, Kristofferson, Scott, David A., Verma, Sachin, Feng, Yongmei, Larue, Lionel, Sahu, Avinash D, Topisirovic, Ivan, Ruppin, Eytan, Ronai, Ze’ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307327/
https://www.ncbi.nlm.nih.gov/pubmed/31740775
http://dx.doi.org/10.1038/s41556-019-0415-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307327/
https://www.ncbi.nlm.nih.gov/pubmed/31740775
http://dx.doi.org/10.1038/s41556-019-0415-1

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