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LCZ696 mitigates diabetic-induced nephropathy through inhibiting oxidative stress, NF-κB mediated inflammation and glomerulosclerosis in rats

BACKGROUND: Diabetic nephropathy (DN) is among the most common microvascular complications of diabetes resulting in end-stage renal disease and therefore search for candidates which can ameliorate the kidney function is needed simultaneously with standard diabetic pharmacotherapy. The current study...

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Detalles Bibliográficos
Autores principales: Mohany, Mohamed, Alanazi, Ahmed Z., Alqahtani, Faleh, Belali, Osamah M., Ahmed, Mohammed M., Al-Rejaie, Salim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307563/
https://www.ncbi.nlm.nih.gov/pubmed/32596035
http://dx.doi.org/10.7717/peerj.9196