Long-term reversal of diabetes by subcutaneous transplantation of pancreatic islet cells and adipose-derived stem cell sheet using surface-immobilized heparin and engineered collagen scaffold

OBJECTIVE: Esterified collagen (EC) can be functionalized with heparin to enhance islet graft stability. Growth factors secreted by human adipose-derived stem cells (hADSCs) can bind efficiently to EC-heparin (EC-Hep), which enhances revascularization and cell protection. We investigated the therape...

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Detalles Bibliográficos
Autores principales: Kim, Yang Hee, Ko, Jae Hyung, Lee, Song, Oh, Ju Yun, Jeong, Gi Seok, Park, Si-Nae, Shim, In Kyong, Kim, Song Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307580/
https://www.ncbi.nlm.nih.gov/pubmed/32565421
http://dx.doi.org/10.1136/bmjdrc-2019-001128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307580/
https://www.ncbi.nlm.nih.gov/pubmed/32565421
http://dx.doi.org/10.1136/bmjdrc-2019-001128

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