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Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation

Mild hypothermia (MH) and edaravone (EDA) exert neuroprotective effects against cerebral ischemia/reperfusion (I/R) injury through activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. However, whether MH and EDA exert synergistic effects against cerebral I/R injury remains u...

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Detalles Bibliográficos
Autores principales: Yu, Hang, Wu, Zhidian, Wang, Xiaozhi, Gao, Chang, Liu, Run, Kang, Fuxin, Dai, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307586/
https://www.ncbi.nlm.nih.gov/pubmed/32626935
http://dx.doi.org/10.3892/ijo.2020.5077