Cargando…

Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation

Mild hypothermia (MH) and edaravone (EDA) exert neuroprotective effects against cerebral ischemia/reperfusion (I/R) injury through activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. However, whether MH and EDA exert synergistic effects against cerebral I/R injury remains u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Hang, Wu, Zhidian, Wang, Xiaozhi, Gao, Chang, Liu, Run, Kang, Fuxin, Dai, Mingming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307586/ https://www.ncbi.nlm.nih.gov/pubmed/32626935 http://dx.doi.org/10.3892/ijo.2020.5077

Ejemplares similares

Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice
por: Xu, Lili, et al.
Publicado: (2022)

Metabolomic Profiling of Brain Protective Effect of Edaravone on Cerebral Ischemia-Reperfusion Injury in Mice
por: Ma, Hui-fen, et al.
Publicado: (2022)

Protective effects of combined treatment with ciprofol and mild therapeutic hypothermia during cerebral ischemia-reperfusion injury
por: Wang, Yi-Chao, et al.
Publicado: (2023)

Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury
por: Fukuta, Tatsuya, et al.
Publicado: (2023)

Proteome profiling of hippocampus reveals the neuroprotective effect of mild hypothermia on global cerebral ischemia–reperfusion injury in rats
por: Wang, Jiajia, et al.
Publicado: (2023)

Mild therapeutic hypothermia protects against cerebral ischemia/reperfusion injury by inhibiting miR-15b expression in rats
por: Liu, Xiangrong, et al.
Publicado: (2017)

Analysis of microRNA expression in cerebral ischemia/reperfusion after mild therapeutic hypothermia treatment in rats
por: Zhao, Shangfeng, et al.
Publicado: (2021)

Protective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb
por: Hori, Kazuichiro, et al.
Publicado: (2013)

Cerebral Tissue Oxidative Ischemia-Reperfusion Injury in Connection with Experimental Cardiac Arrest and Cardiopulmonary Resuscitation: Effect of Mild Hypothermia and Methylene Blue
por: Wiklund, Lars, et al.
Publicado: (2017)

Mild hypothermia reduces expression of Fas/FasL and MMP-3 after cerebral ischemia-reperfusion in rats
por: Zhao, Jingkun, et al.
Publicado: (2014)

Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP
por: Liu, Xiangrong, et al.
Publicado: (2018)

Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia
por: Deguchi, Kentaro, et al.
Publicado: (2014)

Hydrogen sulphide and mild hypothermia activate the CREB signaling pathway and prevent ischemia-reperfusion injury
por: Dai, Hai-bin, et al.
Publicado: (2015)

Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive
por: Kohlhauer, M., et al.
Publicado: (2019)

Fundamental research progress of mild hypothermia in cerebral protection
por: Bao, Long, et al.
Publicado: (2013)

The pathways by which mild hypothermia inhibits neuronal apoptosis following ischemia/reperfusion injury
por: Luo, Chun, et al.
Publicado: (2015)

The Role of Nrf2 in Relieving Cerebral Ischemia-Reperfusion Injury
por: Sun, Yu, et al.
Publicado: (2023)

Palmatine Protects against Cerebral Ischemia/Reperfusion Injury by Activation of the AMPK/Nrf2 Pathway
por: Tang, Chaoliang, et al.
Publicado: (2021)

Correction to: Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive
por: Kohlhauer, M., et al.
Publicado: (2019)

DCA Protects against Oxidation Injury Attributed to Cerebral Ischemia-Reperfusion by Regulating Glycolysis through PDK2-PDH-Nrf2 Axis
por: Zhao, Xiaoyong, et al.
Publicado: (2021)

Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway
por: Liu, Dequan, et al.
Publicado: (2020)

Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation—an experimental study
por: Martins, Rui Miguel, et al.
Publicado: (2019)

Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro
por: Chen, Miao, et al.
Publicado: (2017)

Effects of hypothermia on skeletal ischemia reperfusion injury in rats
por: Ekinci, Şafak, et al.
Publicado: (2015)

Nrf2 protects against cerebral ischemia-reperfusion injury by suppressing programmed necrosis and inflammatory signaling pathways
por: Chen, Weiwei, et al.
Publicado: (2022)

Mild hypothermia pretreatment protects against liver ischemia reperfusion injury via the PI3K/AKT/FOXO3a pathway
por: Xiao, Qi, et al.
Publicado: (2017)

A Nitric Oxide-Donor Furoxan Moiety Improves the Efficacy of Edaravone against Early Renal Dysfunction and Injury Evoked by Ischemia/Reperfusion
por: Chiazza, Fausto, et al.
Publicado: (2015)

Hypothermia selectively protects the anterior forebrain mesocircuit during global cerebral ischemia
por: Wang, Xiao-Hua, et al.
Publicado: (2021)

Uric Acid Protects against Focal Cerebral Ischemia/Reperfusion-Induced Oxidative Stress via Activating Nrf2 and Regulating Neurotrophic Factor Expression
por: Ya, Bai-liu, et al.
Publicado: (2018)

Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway
por: Yang, Yuan, et al.
Publicado: (2022)

Mild Therapeutic Hypothermia Protects from Acute and Chronic Renal Ischemia-Reperfusion Injury in Mice by Mitigated Mitochondrial Dysfunction and Modulation of Local and Systemic Inflammation
por: Schleef, Maxime, et al.
Publicado: (2022)

Bone mesenchymal stem cells transplantation combined with mild hypothermia improves the prognosis of cerebral ischemia in rats
por: Bi, Min, et al.
Publicado: (2018)

Protective effect of edaravone on blood-brain barrier by affecting NRF-2/HO-1 signaling pathway
por: Liu, Jing, et al.
Publicado: (2019)

Protective roles of intra-arterial mild hypothermia and arterial thrombolysis in acute cerebral infarction
por: Peng, Xiaoxiang, et al.
Publicado: (2016)

Protective Effect of Anthocyanin on Neurovascular Unit in Cerebral Ischemia/Reperfusion Injury in Rats
por: Pan, Zihao, et al.
Publicado: (2018)

Edaravone alleviates cell apoptosis and mitochondrial injury in ischemia–reperfusion-induced kidney injury via the JAK/STAT pathway
por: Zhao, Xiaoying, et al.
Publicado: (2020)

Edaravone Ameliorates Renal Warm Ischemia-Reperfusion Injury by Downregulating Endoplasmic Reticulum Stress in a Rat Resuscitation Model
por: Fu, Zhao-Yin, et al.
Publicado: (2020)

Deep Learning Reconstruction Algorithm-Based MRI Image Evaluation of Edaravone in the Treatment of Lower Limb Ischemia-Reperfusion Injury
por: Liu, Jianping, et al.
Publicado: (2022)

Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Rats
por: Singh, Sanjiv, et al.
Publicado: (2019)

Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice★
por: Wang, Hongbo, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_027v883sr13nduo2eg80qji83i