Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments

Occurrence of Lewy bodies (LBs)/Lewy neurites (LNs) containing misfolded fibrillar α-synuclein (α-syn) is one of the pathologic hallmarks of memory impairment-linked synucleinopathies, such as Parkinson’s disease (PD) and dementia with LBs (DLB). While it has been shown that brainstem LBs may contri...

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Detalles Bibliográficos
Autores principales: Kasongo, Danielle Walu, de Leo, Gioacchino, Vicario, Nunzio, Leanza, Giampiero, Legname, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307628/
https://www.ncbi.nlm.nih.gov/pubmed/32393581
http://dx.doi.org/10.1523/ENEURO.0009-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307628/
https://www.ncbi.nlm.nih.gov/pubmed/32393581
http://dx.doi.org/10.1523/ENEURO.0009-20.2020

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