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Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments
Occurrence of Lewy bodies (LBs)/Lewy neurites (LNs) containing misfolded fibrillar α-synuclein (α-syn) is one of the pathologic hallmarks of memory impairment-linked synucleinopathies, such as Parkinson’s disease (PD) and dementia with LBs (DLB). While it has been shown that brainstem LBs may contri...
Autores principales: | Kasongo, Danielle Walu, de Leo, Gioacchino, Vicario, Nunzio, Leanza, Giampiero, Legname, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307628/ https://www.ncbi.nlm.nih.gov/pubmed/32393581 http://dx.doi.org/10.1523/ENEURO.0009-20.2020 |
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