Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis

OBJECTIVE: This study investigated the effect of hUC-MSCs on osteoarthritis (OA) progression in a xenogeneic model. DESIGN: Male, 10 week-old C57BL/6 mice underwent sham surgery (n = 15) or partial medial meniscectomy (PMM; n = 76). 5x10(5) hUC-MSCs (from 3 donors: D1, D2 and D3) were phenotyped via...

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Detalles Bibliográficos
Autores principales: Perry, J., McCarthy, H.S., Bou-Gharios, G., van 't Hof, R., Milner, P.I., Mennan, C., Roberts, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307639/
https://www.ncbi.nlm.nih.gov/pubmed/32596691
http://dx.doi.org/10.1016/j.ocarto.2020.100044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307639/
https://www.ncbi.nlm.nih.gov/pubmed/32596691
http://dx.doi.org/10.1016/j.ocarto.2020.100044

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