Cargando…

Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis

OBJECTIVE: This study investigated the effect of hUC-MSCs on osteoarthritis (OA) progression in a xenogeneic model. DESIGN: Male, 10 week-old C57BL/6 mice underwent sham surgery (n = 15) or partial medial meniscectomy (PMM; n = 76). 5x10(5) hUC-MSCs (from 3 donors: D1, D2 and D3) were phenotyped via...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perry, J., McCarthy, H.S., Bou-Gharios, G., van 't Hof, R., Milner, P.I., Mennan, C., Roberts, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307639/ https://www.ncbi.nlm.nih.gov/pubmed/32596691 http://dx.doi.org/10.1016/j.ocarto.2020.100044

Ejemplares similares

Mesenchymal stromal cells derived from whole human umbilical cord exhibit similar properties to those derived from Wharton's jelly and bone marrow
por: Mennan, Claire, et al.
Publicado: (2016)

Pro-Inflammatory Priming of Umbilical Cord Mesenchymal Stromal Cells Alters the Protein Cargo of Their Extracellular Vesicles
por: Hyland, Mairead, et al.
Publicado: (2020)

Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model
por: Perry, Jade, et al.
Publicado: (2021)

Isolation and Characterisation of Mesenchymal Stem Cells from Different Regions of the Human Umbilical Cord
por: Mennan, Claire, et al.
Publicado: (2013)

Extracellular Vesicle Depletion Protocols of Foetal Bovine Serum Influence Umbilical Cord Mesenchymal Stromal Cell Phenotype, Immunomodulation, and Particle Release
por: Davies, Rebecca, et al.
Publicado: (2023)

A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells
por: Mennan, Claire, et al.
Publicado: (2019)

The anterior cruciate ligament in murine post-traumatic osteoarthritis: markers and mechanics
por: Ramos-Mucci, Lorenzo, et al.
Publicado: (2022)

Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming
por: Hyland, Mairead, et al.
Publicado: (2023)

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis
por: Gardiner, M.D., et al.
Publicado: (2015)

Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis
por: Yamamoto, Kazuhiro, et al.
Publicado: (2020)

Allantoic cyst – an unusual umbilical cord swelling
por: Gupta, N, et al.
Publicado: (2011)

Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis
por: Ramos-Mucci, Lorenzo, et al.
Publicado: (2020)

Progress in the treatment of osteoarthritis with umbilical cord stem cells
por: Liang, Hanguang, et al.
Publicado: (2020)

Human umbilical cord mesenchymal stromal cells in regenerative medicine
por: Detamore, Michael S
Publicado: (2013)

Umbilical Cord Mesenchymal Stromal Cells for Cartilage Regeneration Applications
por: Russo, E., et al.
Publicado: (2022)

Umbilical cord mesenchymal stromal cells—from bench to bedside
por: Chetty, Shashank, et al.
Publicado: (2022)

Post-traumatic osteoarthritis development is not modified by postnatal chondrocyte deletion of Ccn2
por: Keenan, Craig M., et al.
Publicado: (2020)

Allogenic Umbilical Cord Tissue as a Scaffold for Ankle Osteoarthritis
por: Gupta, Ashim, et al.
Publicado: (2023)

Organic Spirality—The Umbilical Cord
por: Roberts, John Rhiwen
Publicado: (1865)

Therapeutic angiogenesis induced by human umbilical cord tissue-derived mesenchymal stromal cells in a murine model of hindlimb ischemia
por: Pereira, Ana Rita S., et al.
Publicado: (2016)

Serum-Free Medium Enhances the Therapeutic Effects of Umbilical Cord Mesenchymal Stromal Cells on a Murine Model for Acute Colitis
por: Wu, Xiaoyun, et al.
Publicado: (2020)

Cell therapy for cartilage repair
por: Hulme, Charlotte H., et al.
Publicado: (2021)

Umbilical Cord PRP vs. Autologous PRP for the Treatment of Hip Osteoarthritis
por: Mazzotta, Alessandro, et al.
Publicado: (2022)

Off-the-shelf mesenchymal stromal cells derived from umbilical cord tissue
por: Oliver-Vila, Irene, et al.
Publicado: (2015)

Urothelial Differentiation of Human Umbilical Cord-Derived Mesenchymal Stromal Cells In Vitro
por: Wu, Shuai, et al.
Publicado: (2013)

Intraperitoneally Delivered Umbilical Cord Lining Mesenchymal Stromal Cells Improve Survival and Kidney Function in Murine Lupus via Myeloid Pathway Targeting
por: Chua, Alvin Wen Choong, et al.
Publicado: (2022)

Abstract 4 Umbilical Cord-Derived Mesenchymal Stromal Cells Suppress Neuroinflammation and Promote Remyelination in the Spinal Cord
por: Min, Hyunjung, et al.
Publicado: (2022)

Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood serum in prostate cancer progression
por: Sousa, André, et al.
Publicado: (2023)

Intramuscular Transplantation of Allogeneic Mesenchymal Stromal Cells Derived from Equine Umbilical Cord
por: Dias, Marianne Camargos, et al.
Publicado: (2016)

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
por: Beeravolu, Naimisha, et al.
Publicado: (2017)

Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
por: Selich, Anton, et al.
Publicado: (2019)

The Potentiality of Human Umbilical Cord Isolated Mesenchymal Stem/Stromal Cells for Cardiomyocyte Generation
por: Abou-ElNaga, Amoura, et al.
Publicado: (2020)

Mesenchymal Stromal Cells from Different Parts of Umbilical Cord: Approach to Comparison & Characteristics
por: Semenova, Ekaterina, et al.
Publicado: (2021)

Umbilical Cord–Derived Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review
por: Dhillon, Jaydeep, et al.
Publicado: (2022)

Pregnancy and umbilical cord pathology: structural and functional parameters of the umbilical cord
por: Dubetskyi, Bohdan Ihorovych, et al.
Publicado: (2023)

Intraarterial transplantation of human umbilical cord blood mononuclear cells is more efficacious and safer compared with umbilical cord mesenchymal stromal cells in a rodent stroke model
por: Karlupia, Neha, et al.
Publicado: (2014)

Xeno-free culture condition for human bone marrow and umbilical cord matrix-derived mesenchymal stem/stromal cells using human umbilical cord blood serum
por: Esmaeli, Azadeh, et al.
Publicado: (2016)

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis
por: Nakamura, Hiroyuki, et al.
Publicado: (2020)

Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential
por: Mennan, Claire, et al.
Publicado: (2018)

Umbilical cord accidents
por: Collins, Jason H
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gt2c41bbq52uf4hg1ddhbcj3dm