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Photodepletion with 2-Se-Cl prevents lethal graft-versus-host disease while preserving antitumor immunity
Acute graft-versus-host-disease (GVHD), limits the use of hematopoietic cell transplant (HCT) to treat a variety of malignancies. Any new therapeutic approach must satisfy three requirements: 1) Prevent GVHD, 2) Maintain anti-pathogen immunity, and 3) Maintain anti-tumor immunity. In prior studies w...
Autores principales: | Grayson, Jason M., Perez, Mildred D., Blevins, Rebecca, Coe, Benjamin N., Detty, Michael R., McIver, Zachariah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307732/ https://www.ncbi.nlm.nih.gov/pubmed/32569289 http://dx.doi.org/10.1371/journal.pone.0234778 |
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