Photodepletion with 2-Se-Cl prevents lethal graft-versus-host disease while preserving antitumor immunity

Acute graft-versus-host-disease (GVHD), limits the use of hematopoietic cell transplant (HCT) to treat a variety of malignancies. Any new therapeutic approach must satisfy three requirements: 1) Prevent GVHD, 2) Maintain anti-pathogen immunity, and 3) Maintain anti-tumor immunity. In prior studies w...

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Detalles Bibliográficos
Autores principales: Grayson, Jason M., Perez, Mildred D., Blevins, Rebecca, Coe, Benjamin N., Detty, Michael R., McIver, Zachariah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307732/
https://www.ncbi.nlm.nih.gov/pubmed/32569289
http://dx.doi.org/10.1371/journal.pone.0234778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307732/
https://www.ncbi.nlm.nih.gov/pubmed/32569289
http://dx.doi.org/10.1371/journal.pone.0234778

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