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NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure

Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral disorders and cancer in offspring, but the mechanism has not been identified. Here we use mouse models to investigate mechanisms and impacts of paternal CS exposure. We demonstrate that CS exposure induces sperm D...

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Detalles Bibliográficos
Autores principales: Murphy, Patrick J., Guo, Jingtao, Jenkins, Timothy G., James, Emma R., Hoidal, John R., Huecksteadt, Thomas, Broberg, Dallin S., Hotaling, James M., Alonso, David F., Carrell, Douglas T., Cairns, Bradley R., Aston, Kenneth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307791/
https://www.ncbi.nlm.nih.gov/pubmed/32520939
http://dx.doi.org/10.1371/journal.pgen.1008756