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NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure
Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral disorders and cancer in offspring, but the mechanism has not been identified. Here we use mouse models to investigate mechanisms and impacts of paternal CS exposure. We demonstrate that CS exposure induces sperm D...
Autores principales: | Murphy, Patrick J., Guo, Jingtao, Jenkins, Timothy G., James, Emma R., Hoidal, John R., Huecksteadt, Thomas, Broberg, Dallin S., Hotaling, James M., Alonso, David F., Carrell, Douglas T., Cairns, Bradley R., Aston, Kenneth I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307791/ https://www.ncbi.nlm.nih.gov/pubmed/32520939 http://dx.doi.org/10.1371/journal.pgen.1008756 |
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