IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival

In the tumor microenvironment, local immune dysregulation is driven in part by macrophages and dendritic cells that are polarized to a mixed proinflammatory/immune-suppressive phenotype. The unfolded protein response (UPR) is emerging as the possible origin of these events. Here we report that the i...

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Detalles Bibliográficos
Autores principales: Batista, Alyssa, Rodvold, Jeffrey J., Xian, Su, Searles, Stephen C., Lew, Alyssa, Iwawaki, Takao, Almanza, Gonzalo, Waller, T. Cameron, Lin, Jonathan, Jepsen, Kristen, Carter, Hannah, Zanetti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307794/
https://www.ncbi.nlm.nih.gov/pubmed/32520957
http://dx.doi.org/10.1371/journal.pbio.3000687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307794/
https://www.ncbi.nlm.nih.gov/pubmed/32520957
http://dx.doi.org/10.1371/journal.pbio.3000687

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