Ursolic acid protects against cisplatin-induced ototoxicity by inhibiting oxidative stress and TRPV1-mediated Ca(2+)-signaling

Cisplatin (CDDP) is widely used in clinical settings for the treatment of various cancers. However, ototoxicity is a major side effect of CDDP, and there is an associated risk of irreversible hearing loss. We previously demonstrated that CDDP could induce ototoxicity via activation of the transient...

Descripción completa

Detalles Bibliográficos
Autores principales: Di, Yang, Xu, Tao, Tian, Yuan, Ma, Tingting, Qu, Donghao, Wang, Yan, Lin, Yuhan, Bao, Dongyan, Yu, Li, Liu, Shuangyue, Wang, Aimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307815/
https://www.ncbi.nlm.nih.gov/pubmed/32626955
http://dx.doi.org/10.3892/ijmm.2020.4633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307815/
https://www.ncbi.nlm.nih.gov/pubmed/32626955
http://dx.doi.org/10.3892/ijmm.2020.4633

Ejemplares similares