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Simvastatin inhibits the adipogenesis of bone marrow-derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling

Simvastatin is effective in the treatment of osteoporosis, partly through the inhibition of the adipogenesis of bone-marrow derived mesenchymal stem cells (BMSCs). The present study focused on the mechanisms responsible for the inhibitory effects of simvastatin on adipogenesis and examined the effec...

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Detalles Bibliográficos
Autores principales: Guo, Yao, Huo, Jianzhong, Wu, Dou, Hao, Haihu, Ji, Xinghua, Zhao, Enzhe, Nie, Boyuan, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307816/
https://www.ncbi.nlm.nih.gov/pubmed/32468037
http://dx.doi.org/10.3892/ijmm.2020.4606