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Simvastatin inhibits the adipogenesis of bone marrow-derived mesenchymal stem cells through the downregulation of chemerin/CMKLR1 signaling
Simvastatin is effective in the treatment of osteoporosis, partly through the inhibition of the adipogenesis of bone-marrow derived mesenchymal stem cells (BMSCs). The present study focused on the mechanisms responsible for the inhibitory effects of simvastatin on adipogenesis and examined the effec...
Autores principales: | Guo, Yao, Huo, Jianzhong, Wu, Dou, Hao, Haihu, Ji, Xinghua, Zhao, Enzhe, Nie, Boyuan, Liu, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307816/ https://www.ncbi.nlm.nih.gov/pubmed/32468037 http://dx.doi.org/10.3892/ijmm.2020.4606 |
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