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Effect of Pressure Increase on Macromolecules’ Adsorption in Ion Exchange Chromatography
[Image: see text] In this study a new method for evaluating the pressure effect on separations of oligonucleotides and proteins on an anion exchange column was developed. The pressure rise of up to 500 bar was attained by coupling restriction capillaries to the column outlet to minimize differences...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307832/ https://www.ncbi.nlm.nih.gov/pubmed/32075366 http://dx.doi.org/10.1021/acs.analchem.9b05729 |