IL-27 suppresses airway inflammation, hyperresponsiveness and remodeling via the STAT1 and STAT3 pathways in mice with allergic asthma

Type 2 cytokine-associated immunity may be involved in the pathogenesis of allergic asthma. Although interleukin 27 (IL-27) has been reported as an initiator and suppressor of T-helper 1 (Th1) and T-helper 2 (Th2) responses, respectively, its effects on the development of asthma remain unclear. In t...

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Detalles Bibliográficos
Autores principales: Lu, Degan, Lu, Jiameng, Ji, Xiaoqing, Ji, Yanbo, Zhang, Zewen, Peng, Haiying, Sun, Fei, Zhang, Caiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307842/
https://www.ncbi.nlm.nih.gov/pubmed/32626920
http://dx.doi.org/10.3892/ijmm.2020.4622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307842/
https://www.ncbi.nlm.nih.gov/pubmed/32626920
http://dx.doi.org/10.3892/ijmm.2020.4622

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