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Hyperoxia reduces STX17 expression and inhibits the autophagic flux in alveolar type II epithelial cells in newborn rats

Supplemental oxygen therapy can be life-saving for premature infants. Our previous study revealed a defect in the autophagic flux in the lung tissues of neonatal rats with hyperoxia-induced bronchopulmonary dysplasia (BPD), but the underlying mechanism remains unknown. Moreover, there are few innova...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Zhao, Xinyi, Zhang, Dingning, Gao, Siyang, Xue, Xindong, Fu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307846/
https://www.ncbi.nlm.nih.gov/pubmed/32467992
http://dx.doi.org/10.3892/ijmm.2020.4617