Cargando…

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential target for cancer therapy, owing to its ability to selectively kill cancer cells without causing significant toxicity to normal cells. However, due to the lack of death receptor expression, cancer cells can become highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zinnah, Kazi Mohammad Ali, Seol, Jae-Won, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307864/
https://www.ncbi.nlm.nih.gov/pubmed/32626921
http://dx.doi.org/10.3892/ijmm.2020.4635