Cargando…
Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential target for cancer therapy, owing to its ability to selectively kill cancer cells without causing significant toxicity to normal cells. However, due to the lack of death receptor expression, cancer cells can become highly...
Autores principales: | Zinnah, Kazi Mohammad Ali, Seol, Jae-Won, Park, Sang-Youel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307864/ https://www.ncbi.nlm.nih.gov/pubmed/32626921 http://dx.doi.org/10.3892/ijmm.2020.4635 |
Ejemplares similares
-
Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline
por: Zinnah, K.M.A., et al.
Publicado: (2021) -
Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation
por: Kim, Sung-Wook, et al.
Publicado: (2015) -
PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux
por: Nazim, Uddin MD., et al.
Publicado: (2017) -
Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux
por: Nazim, Uddin Md, et al.
Publicado: (2020) -
Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS
por: Nazim, Uddin MD., et al.
Publicado: (2019)