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Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks

[Image: see text] In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here cyclic oligochalcogenides (COCs), are covalently attached to lysines of wild-type streptavidin....

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Detalles Bibliográficos
Autores principales: López-Andarias, Javier, Saarbach, Jacques, Moreau, Dimitri, Cheng, Yangyang, Derivery, Emmanuel, Laurent, Quentin, González-Gaitán, Marcos, Winssinger, Nicolas, Sakai, Naomi, Matile, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307903/
https://www.ncbi.nlm.nih.gov/pubmed/32109058
http://dx.doi.org/10.1021/jacs.9b13621