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Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks
[Image: see text] In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here cyclic oligochalcogenides (COCs), are covalently attached to lysines of wild-type streptavidin....
Autores principales: | López-Andarias, Javier, Saarbach, Jacques, Moreau, Dimitri, Cheng, Yangyang, Derivery, Emmanuel, Laurent, Quentin, González-Gaitán, Marcos, Winssinger, Nicolas, Sakai, Naomi, Matile, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307903/ https://www.ncbi.nlm.nih.gov/pubmed/32109058 http://dx.doi.org/10.1021/jacs.9b13621 |
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