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Silver-Assisted [3 + 2] Annulation of Nitrones with Isocyanides: Synthesis of 2,3,4-Trisubstituted 1,2,4-Oxadiazolidin-5-ones

[Image: see text] A silver-assisted method for [3 + 2] annulation of nitrones with isocyanides has been developed. The developed protocol allows access to a variety of 2,3,4-trisubstituted 1,2,4-oxadiazolidin-5-one derivatives as single diastereomers in good to excellent yields using silver oxide as...

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Detalles Bibliográficos
Autores principales: Shen, Xuanyu, Shatskiy, Andrey, Chen, Yan, Kärkäs, Markus D., Wang, Xiang-Shan, Liu, Jian-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307928/
https://www.ncbi.nlm.nih.gov/pubmed/32013428
http://dx.doi.org/10.1021/acs.joc.9b03279