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Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

[Image: see text] The resurgence of interest in monoamine oxidases (MAOs) has been fueled by recent correlations of this enzymatic activity with cardiovascular, neurological, and oncological disorders. This has promoted increased research into selective MAO-A and MAO-B inhibitors. Here, we shed ligh...

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Detalles Bibliográficos
Autores principales: Knez, Damijan, Colettis, Natalia, Iacovino, Luca G., Sova, Matej, Pišlar, Anja, Konc, Janez, Lešnik, Samo, Higgs, Josefina, Kamecki, Fabiola, Mangialavori, Irene, Dolšak, Ana, Žakelj, Simon, Trontelj, Jurij, Kos, Janko, Binda, Claudia, Marder, Mariel, Gobec, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307930/
https://www.ncbi.nlm.nih.gov/pubmed/31917923
http://dx.doi.org/10.1021/acs.jmedchem.9b01886